Synthesis, characterization and antimicrobial screening of quinoline based quinazolinone-4-thiazolidinone heterocycles
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چکیده
منابع مشابه
Synthesis, characterization and antimicrobial screening of novel quinoline-thiazole derivatives
2-Chloroquinoline-3-carbaldehyde 1 reacts with 2-cyanoacetohydrazide in ethanol to result in 1-[1-aza-2-(2-chloro(3quinolyl))vinyl]-2-cyanoacetamide 2. Phenyl isothiocyanate added to a stirred solution of compound 2, sulphur and triethylamine in a mixed solvent of dimethylformamide : ethanol to result in N-[1-aza-2-(2-chloro(3-quinolyl))vinyl](4amino-3-phenyl-2-thioxo(1,3-thiazoline-5-yl)) carb...
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15 صفحه اولNovel 4-Thiazolidinone Derivatives as Anti-Infective Agents: Synthesis, Characterization, and Antimicrobial Evaluation.
A series of new 4-thiazolidinone derivatives was synthesized, characterized by spectral techniques, and screened for antimicrobial activity. All the compounds were evaluated against five Gram-positive bacteria, two Gram-negative bacteria, and two fungi, at concentrations of 50, 100, 200, 400, 800, and 1600 µg/mL, respectively. Minimum inhibitory concentrations of all the compounds were also det...
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In recent years, there has been a rising interest in researching and finding new antimicrobial agents from various sources to fight against microbial infectious pathogens. Therefore, a greater attention has been paid to synthesize new molecules. In this regarding a straightforward two-step protocol for the synthesis of 2,3-disubstituted-4-thiazolidinone (4a-f) and 2,3disubstituted-5-methyl-4-th...
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Two series of 2–(4–cyanophenyl amino)–4–quinoline (quinazoline)–4–yloxy–6–piperazinyl (piperidinyl)–1,3,5–triazines were synthesized so as to investigate their antimicrobial and antitubercular action. Newer analogues were characterized by IR, H NMR spectroscopy and elemental analyses. Pharmacological screening against eight bacteria (S. aureus, B. cereus, E. coli, P. aeruginosa, K. pneumoniae, ...
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ژورنال
عنوان ژورنال: Arabian Journal of Chemistry
سال: 2014
ISSN: 1878-5352
DOI: 10.1016/j.arabjc.2011.08.007